Cord Tissue Cryopreservation
The umbilical cord is the line of life between mother and child. It contains many blood vessels in which the umbilical cord blood is throbbing. In order for the blood vessels to withstand stress , they are covered by umbilical cord tissue that protects and supports the cord.
Umbilical cord tissue (Wharton’s gelly) contains a particularly large number of mesenchymal stem cells, making this biological material particularly valuable and important for potential future stem cell therapies and applications for the potential treatment of serious illnesses.
At present, many clinical trials are under way in the world on the potential use of mesenchymal cells for the treatment of diseases and for regenerative medicine (vascular diseases, autoimmune diseases, joint arthritis etc. In addition, mesenchymal stem cells may potentially inhibit unwanted immune system responses and thus reduce rejection after allogeneic transplantation. Graft versus host disease (GvHD) is unfortunately still an unpleasant complication.
Today, it is already beginning to be seen that autologous mesenchymal stem cells will be most frequently applied by allogeneic donor stem cells. The fields of research in regenerative medicine are in any case significant and promising. With the development of research and technology, doctors, experts and scientists are hoping to discover even more extensive therapeutic options.
Collection and Cryopreservation Procedure
The process of storing umbilical cord tissue starts from the maternity hospital and is particularly easy and painless. After the umbilical cord has been cut off, the blood is first collected and then the doctor or midwife cuts the umbilical cord near the placenta to get as much of it as possible.
The greatest risk in the process of storing umbilical cord tissue is the growth of microbes. Natural delivery does not take place in a sterile environment. In order not to later affect the quality of the stem cell preparation, Omnigen attempts to minimize exposure to bacteria already during transport. The umbilical cord is placed in the special sterile vial contained in the collection KIT and sent to the Omnigen laboratories.
When the umbilical cord reaches the laboratory, it is well disinfected, cleaned and washed.
Subsequently, part of the umbilical cord will be cultivated to test for possible microbial infections. The major part of the tissue will be cryopreserved in specific vials in liquid nitrogen.
For the long-term cryopreservation of the tissue, a high-tech controlled freezing machine is used, which, by computer and special programs, reduces the temperature gradually and with absolute precision, so that there is no risk to cells viability. In this way, tissue samples gradually reach a very low temperature, then placed in special storage tanks containing liquid nitrogen at a temperature not higher than -150 ° C.
Cryopreservation tanks are the most modern devices in the field of biotechnology. These devices temperatures are monitored by special electronic systems 24 hours a day and record the storage temperature of the samples constantly. The storage rooms are monitored by cameras that continuously record every movement in the company’s premises, ensuring maximum safety.
Moreover, we can guarantee the uninterrupted operation of all devices, even after prolonged power failure, by using a sophisticated external generator installed in our facilities. Essentially Omnigen can currently produce all the power needed for its operation without depending on any power company.
Omnigen is one of the few companies in Greece with that infrastructure.
Furthermore, the scientific staff of our company can ensure fast isolation and storage of your baby’s stem cells 365 days per year. It is known that maximal viability of stem cells is achieved the soonest we process the cord blood (best within 48 hours).
Studies published in reputable scientific magazines indicate that the viability of stem cells (i.e. the number of cells that remain alive) depends on the time lap between collection and storage. Some companies send the sample to a foreign country for treatment and storage. These companies cannot in any case guarantee completion of the process within the first 24 hours.
Disclaimer: Omnigen is making every effort to provide complete and specialized services by offering the real benefits of science to man, constantly pursuing ongoing development. Acting in the field of stem cell cryopreservation, cell therapy and regenerative medicine, we make every effort to include accurate and reliable information both on our website and on printed material. However, Omnigen does not give any guarantee, express or implied, nor does it give any promises regarding the effect of cell therapies, their usefulness, their potential beneficial effects, and their suitability to cure any disease. Omnigen’s information material and the information it provides should not be used as a substitute for medical guidance, counseling, diagnosis or treatment of any disease or disorder. The user of any therapies assumes any risk that may arise from participating in them. Omnigen accepts no responsibility for any loss or damage caused as a direct or indirect consequence of the use or misuse of the information provided on this website or through the information provided here.